Synthetic approaches to the 2011 new drugs

Hong X Ding; Kevin K-C Liu; Subas M Sakya; Andrew C Flick; Christopher J O'Donnell

doi:10.1016/j.bmc.2013.02.061

Synthetic approaches to the 2011 new drugs

Bioorg Med Chem. 2013 Jun 1;21(11):2795-825. doi: 10.1016/j.bmc.2013.02.061. Epub 2013 Apr 6.

Authors

Hong X Ding¹, Kevin K-C Liu, Subas M Sakya, Andrew C Flick, Christopher J O'Donnell

Affiliation

¹ Shenogen Pharma Group, Beijing, China. Hongxia.ding@shenogen.com

PMID: 23623674
DOI: 10.1016/j.bmc.2013.02.061

Abstract

New drugs are introduced to the market every year and each represents a privileged structure for its biological target. These new chemical entities (NCEs) provide insights into molecular recognition and also serve as leads for designing future new drugs. This review covers the synthesis of 26 NCEs that were launched in the world in 2011.

Publication types

Review

MeSH terms

Drug Approval*
Drug Design*
Humans
Pharmaceutical Preparations / chemical synthesis*

Substances

Pharmaceutical Preparations